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Medical support typically includes pulmonary function testing, CT imaging, and a diagnosis that fits the clinical pattern of fixed small-airway obstruction, with a lung biopsy sometimes used in complex cases

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The R-squared statistic for full, urban and rural samples (0.2962, 0.2777 and 0.4046, respectively) in this study showed that there are other factors that are not included in the model but associated with tobacco consumption in Nigeria

Altogether, these results suggest that FOXI1 + ionocytes, while contributing the densest CFTR and being critical for ion transport homeostasis, are not solely maintaining CFTR activity in the human tracheal epithelium